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Pirtobrutinib 结构式

Pirtobrutinib

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货号 :BCP42730CAS号 :2101700-15-4纯度:98%
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  • 基本信息与产品描述
CAS号 2101700-15-4 货号 BCP42730
中文名 Pirtobrutinib
英文名 Pirtobrutinib
中文别名
英文别名 LOXO-305;LOXO 305;LOXO305;BTK inhibitor 16;
SMILES CC(C(F)(F)F)N1C(=C(C(=N1)C2=CC=C(C=C2)CNC(=O)C3=C(C=CC(=C3)F)OC)C(=O)N)N
化学名称
分子式 C22H21F4N5O3 分子量 479.43
纯度 98% 配送 惯例下常温包邮
产品描述 Pirtobrutinib is an investigational, novel, selective non-covalent Bruton’s tyrosine kinase (BTK) inhibitor. LOXO-305 was designed to reversibly bind BTK, preserve activity in the presence of the acquired resistance, and avoid off-target kinases that have complicated the development of both covalent and investigational non-covalent BTK inhibitors.LOXO-305 is a highly selective, non-covalent BTKi that inhibits both wild type (WT) and C481-mutated BTK with equal low nM potency was developed.
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