BMS-986142

参考资料仅供科学研究，不可用于个人用途。

货号：BCP29622CAS号：1643368-58-4纯度：98%

规格	价格(CNY)	是否现货	购买咨询
5.00 mg	￥6600.00	In-stock	购买咨询
10.00 mg	￥9900.00	In-stock	购买咨询

在线咨询

大批量询价

全国免运费！免费咨询：400-099-8200 或手机联系：13472751340

* 必填项

请填妥以下表格,您将在一分钟内得到邮件机器人给你的报价。

* Required Fields.

Please complete the form below and we will contact you shortly.

* Required Fields.

Please complete the form below and we will contact you shortly.

CAS号	1643368-58-4	货号	BCP29622
中文名	BMS-986142
英文名	BMS-986142
中文别名
英文别名	BMS 986142; BMS986142;
SMILES	O=C(C1=CC(F)=[C@]([C@]2=CC=CC(N3C(N(C)C4=C(C=CC=C4F)C3=O)=O)=C2C)C5=C1NC6=C5CC[C@H](C(C)(O)C)C6)N
化学名称
分子式	C32H30F2N4O4	分子量	572.61
纯度	98%	配送	惯例下常温包邮
产品描述	BMS-986142 is a potent, selective, reversible BTK inhibitor. BMS-986142 shows BTK IC50 = 0.5nM; human WB IC50 = 90 nM. In molecule of BMS-986142, two atropisomeric centers were rotationally locked to provide a single, stable atropisomer, resulting in enhanced potency and selectivity as well as a reduction in safety liabilities. With significantly enhanced potency and selectivity, excellent in vivo properties and efficacy, and a very desirable tolerability and safety profile, BMS-986142 was advanced into clinical studies.