AV-412 Tosylate

参考资料仅供科学研究，不可用于个人用途。

货号：BCP23783CAS号：451493-31-5纯度：98%

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CAS号	451493-31-5	货号	BCP23783
中文名	AV-412 Tosylate
英文名	AV-412 Tosylate
中文别名
英文别名	MP-412; MP 412; MP412; AV-412; AV 412; AV412;
SMILES	O=S(C1=CC=C(C)C=C1)(O)=O.C=CC(NC2=CC3=C(NC4=CC=C(F)C(Cl)=C4)N=CN=C3C=C2C#CC(N5CCN(C)CC5)(C)C)=O.O=S(C6=CC=C(C)C=C6)(O)=O
化学名称
分子式	C41H44ClFN6O7S2	分子量	851.41
纯度	98%	配送	惯例下常温包邮
产品描述	AV-412, also known as MP-412, is a second-generation, orally bioavailable dual kinase inhibitor with potential antineoplastic activity. EGFR/HER2 inhibitor AV-412 binds to and inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2), which may result in the inhibition of tumor growth and angiogenesis, and tumor regression in EGFR/HER2-expressing tumors. This agent may be active against EGFR/HER2-expressing tumor cells that are resistant to first-generation kinase inhibitors. EGFR and HER2 are receptor tyrosine kinases that play major roles in tumor cell proliferation and tumor vascularization.