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CAS号 | 388082-77-7 | 货号 | BCP47521 |
关联产品 | 388082-78-8(二甲苯磺酸拉帕替尼) 231277-92-2(拉帕替尼) | ||
中文名 | 二对甲苯磺酸拉帕替尼 | ||
英文名 | Lapatinib ditosylate | ||
中文别名 | 拉帕替尼二甲苯磺酸盐; | ||
英文别名 | GSK572016; GSK-572016; GSK 572016; GW2016; GW-2016; GW 2016; | ||
SMILES | CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl | ||
化学名称 | |||
分子式 | C43H42ClFN4O10S3 | 分子量 | 925.46 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Lapatinib Ditosylate is the ditosylate salt of lapatinib, a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib is a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types. Check for active clinical trials or closed clinical trials using this agent. |
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