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| CAS号 | 1637542-33-6 | 货号 | BCP30542 |
| 中文名 | Nedisertib | ||
| 英文名 | Nedisertib | ||
| 中文别名 | |||
| 英文别名 | MSC2490484A; MSC-2490484A; MSC 2490484A; M3814; M-3814; M 3814; | ||
| SMILES | COC1=NN=C(C=C1)C(C2=C(C=C(C(=C2)C3=NC=NC4=C3C=CC(=C4)N5CCOCC5)F)Cl)O | ||
| 化学名称 | |||
| 分子式 | C24H21ClFN5O3 | 分子量 | 481.91 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Nedisertib, also known as M-3814, is an orally available inhibitor of DNA-dependent protein kinase (DNA-PK), with potential antineoplastic and chemo/radiosensitizing activities. Upon oral administration, the DNA-PK inhibitor MSC2490484A binds to and inhibits the activity of DNA-PK. This inhibits the ability of tumor cells to repair damaged DNA, which may lead to a reduction in cellular proliferation of cancer cells expressing DNA-PK. | ||
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