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Mobocertinib succinate 结构式

琥珀酸莫博替尼

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP33315CAS号 :2389149-74-8纯度:98%
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  • 基本信息与产品描述
CAS号 2389149-74-8 货号 BCP33315
中文名 琥珀酸莫博替尼
英文名 Mobocertinib succinate
中文别名 莫博替尼琥珀酸;
英文别名 TAK-788 succinate; AP32788 succinate;TAK 788 succinate; AP 32788 succinate;TAK788 succinate; AP-32788 succinate;
SMILES O=C(C1=CN=C(NC2=CC(NC(C=C)=O)=C(N(CCN(C)C)C)C=C2OC)N=C1C3=CN(C)C4=C3C=CC=C4)OC(C)C.O=C(O)CCC(O)=O
化学名称
分子式 C36H45N7O8 分子量 703.78
纯度 98% 配送 惯例下常温包邮
产品描述 Mobocertinib succinate is a potent and orally active inhibitor of EGFR and HER2 oncogenic mutants, including exon 20 insertions, with selectivity over WT EGFR. Antitumor activity.Mobocertinib, also known as TAK-788 and AP32788, is an investigational TKI with potent, selective preclinical activity against activating EGFR and HER2 mutations, including exon 20 insertions. TAK-788 exhibits antitumor activity in pts with EGFR exon 20 insertions with an AE profile consistent with other EGFR TKIs.
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