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Lapatinib Ditosylate 结构式

二甲苯磺酸拉帕替尼

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP01815CAS号 :388082-78-8纯度:98%
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  • 基本信息与产品描述
CAS号 388082-78-8 货号 BCP01815
关联产品 231277-92-2(拉帕替尼) 388082-77-7(二对甲苯磺酸拉帕替尼)
中文名 二甲苯磺酸拉帕替尼
英文名 Lapatinib Ditosylate
中文别名
英文别名 Tykerb Ditosylate;GW572016 ditosylate; GW2016 ditosylate;
SMILES CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl
化学名称
分子式 C29H26ClFN4O4S.2(C7H8O3S) 分子量 925.46
纯度 98% 配送 惯例下常温包邮
产品描述 Lapatinib Ditosylate is the ditosylate salt of lapatinib, a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types.
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