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CAS号 | 388082-78-8 | 货号 | BCP01815 |
关联产品 | 231277-92-2(拉帕替尼) 388082-77-7(二对甲苯磺酸拉帕替尼) | ||
中文名 | 二甲苯磺酸拉帕替尼 | ||
英文名 | Lapatinib Ditosylate | ||
中文别名 | |||
英文别名 | Tykerb Ditosylate;GW572016 ditosylate; GW2016 ditosylate; | ||
SMILES | CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl | ||
化学名称 | |||
分子式 | C29H26ClFN4O4S.2(C7H8O3S) | 分子量 | 925.46 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Lapatinib Ditosylate is the ditosylate salt of lapatinib, a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types. |
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