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Fostamatinib disodium hexahydrate 结构式

福他替尼钠盐六水合物

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP14298CAS号 :914295-16-2纯度:98%
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  • 基本信息与产品描述
CAS号 914295-16-2 货号 BCP14298
关联产品 1025687-58-4(福他替尼二钠盐) 901119-35-5(福他替尼)
中文名 福他替尼钠盐六水合物
英文名 Fostamatinib disodium hexahydrate
中文别名
英文别名 R788 disodium hexahydrate;R 788 disodium hexahydrate;R-788 disodium hexahydrate;
SMILES CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)([O-])[O-])C.O.O.O.O.O.O.[Na+].[Na+]
化学名称
分子式 C23H36FN6Na2O15P 分子量 732.52
纯度 98% 配送 惯例下常温包邮
产品描述 Fostamatinib Disodium is an orally available disodium salt of the Syk kinase inhibitor fostamatinib with potential anti-inflammatory and immunomodulating activities. Fostamatinib inhibits Syk kinase-mediated IgG Fc gamma receptor signaling, resulting in inhibition of the activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage. Syk kinase, widely expressed in hematopoietic cells, is a nonreceptor tyrosine kinase that is involved in coupling activated immunoreceptors to signal downstream events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis.
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