Pyrotinib

参考资料仅供科学研究，不可用于个人用途。

货号：BCP29458CAS号：1269662-73-8纯度：98%

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CAS号	1269662-73-8	货号	BCP29458
关联产品	1397922-61-0（Pyrotinib maleate） 1246089-97-3（Pyrotinib Racemate ）
中文名	Pyrotinib
英文名	Pyrotinib
中文别名
英文别名	SHR-1258; SHR1258; SHR 1258;
SMILES	O=C(NC1=C(OCC)C=C2N=CC(C#N)=C(NC3=CC=C(OCC4=NC=CC=C4)C(Cl)=C3)C2=C1)/C=C/[C@@H]5N(C)CCC5
化学名称
分子式	C32H31ClN6O3	分子量	583.08
纯度	98%	配送	惯例下常温包邮
产品描述	Pyrotinibm, also known as SHR-1258, is an orally bioavailable, dual kinase inhibitor of the epidermal growth factor receptor (EGFR or HER-1) and the human epidermal growth factor receptor 2 (ErbB2 or HER-2), with potential antineoplastic activity. Upon oral administration, pyrotinib binds to and inhibits both EGFR and HER2, which may result in the inhibition of tumor growth and angiogenesis, and tumor regression in EGFR/HER2-expressing tumor cells. EGFR and HER2 are receptor tyrosine kinases that are upregulated in various tumor cell types and play major roles in tumor cell proliferation and tumor vascularization.