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RAR/RXR

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RAR/RXR

结构式 货号 产品名称 CAS号
9-cis-Retinoic acid 结构式
 BCP27899 9-顺式维甲酸 5300-03-8
9-cis-Retinoic acid, a vitamin A derivative, is a potent RAR/RXR agonist. 9-cis-Retinoic acid induces apoptosis, regulates cell cycle and has anticancer, anti-inflammatory and neuroprotection activities.
AGN 196996 结构式
 BCP46996 AGN 196996 958295-17-5
AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM).
PA 452 结构式
 BCP46369 PA 452 457657-34-0
PA 452 is an RXR antagonist.
BMS 195614 结构式
 BCP44394 BMS 195614 253310-42-8
BMS 195614 is a neutral RAR α-selective antagonist (Ki = 2.5 nM) and exhibits no significant effect on nuclear receptor corepressor (NCoR) binding.
EC23 结构式
 BCP38021 EC23 104561-41-3
EC23 is a fluorescent, voltage, indicator, action, potentials, mammalian, neurons, perturbations, cardiac, waveform, pluripotent, stem, cell-derived, cardiomyocytes
BMS453 结构式
 BCP37819 BMS453 166977-43-1
BMS453, a synthetic retinoid, is an RARβ agonist and an RARα/RARγ antagonist. BMS453 inhibits breast cell growth predominantly through the induction of active TGFβ.
AGN193109 结构式
 BCP34864 AGN193109 171746-21-7
AGN193109 is a retinoic acid receptor (RAR) antagonist.
Bigelovin 结构式
 BCP34451 锦菊素 3668-14-2
Bigelovin has been shown to cause cell cycle arrest and subsequently induce apoptosis in cancer cells. It is also known as a potent cytotoxic sesquiterpene lactone from Inula sp.
Trifarotene 结构式
 BCP31392 曲法罗汀 895542-09-3
Trifarotene is a retinoic acid receptor (RAR) agonist with Kdapp of 2, 15 and 500 nM for RARγ, RARβ and RARα, respectively.
Etretinate 结构式
 BCP31125 依曲替酯 54350-48-0
Etretinate is a RAR and RXR agonist previoulsy used to treat psoriasis. It induces brth defects and suppresses proliferation in cutaneous T-cell lymphoma models.
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