所有产品分类
所有产品
信号通路
- Angiogenesis/Protein Tyrosine Kinase
- Apoptosis Pathway
- Cell Cycle/DNA Damage
- Epigenetics
-
GPCR/G Protein
- Urotensin Receptor
- Melatonin Receptor
- Neurotensin Receptor
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- Somatostatin Receptor
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- Bradykinin Receptor
- Guanylate Cyclase
- Melanocortin Receptor
- Imidazoline Receptor
- Neuropeptide Receptor
- PAR
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- Sigma Receptor
- S1P Receptor
- GHSR
- PKA
- OX Receptor
- Adenosine Receptor
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- NK Receptor
- GnRH Receptor
- Leukotriene Receptor
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- mAChR
- P2 Receptor
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- Smoothened/Smo
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- Microbiology/Virology
-
Neuro Signaling Pathway
- Imidazoline Receptor
- Monoamine Oxidase
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- Amyloid β
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- Beta secretase
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- SSRI
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- P glycoprotein
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- Dopamine Transporter
- 5 HT Receptor/Serotonin Receptor
- P2 Receptor
- FAAH
- CGRP Receptor
- nAChR
- COX
- GABA Receptor
- mAChR
- NFκB
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-
Protease/Metabolic Enzyme
- COMT
- 11β HSD
- Carboxypeptidase
- ACC
- Xanthine Oxidase
- Pyruvate Kinase
- Mitochondrial Metabolism
- ALDH
- SCD
- Serine Protease
- MLR
- FTase
- CETP
- Neprilysin
- MAGL
- Carbonic Anhydrase
- E1 E2 E3 Enzyme
- Elastase
- PAI1
- NOX
- ROR
- Glucokinase
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- Tyrosinase
- FAS
- DGAT
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- IDH
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- Phosphatase
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- RAAS/ACE
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- HSP
- Tryptophan Hydroxylase/TPH
- Factor Xa
- DPP
- Procollagen C Proteinase
- Integrase
- Phosphodiesterase/PDE
- Phospholipase
- LXR
- Proteasome
- Cytochrome P450
- TGF beta/Smad
- Wnt/Stem Cell
- Others Pathway
研究领域
- Metabolic Disease
- Neurological Disease
- Endocrinology
- Diabetes
- Cardiovascular Disease
- Immunology
- Allergy
- Inflammation
- Infection
- Cancer
天然产物
抗体
多肽
催化剂
杂质对照品
医药中间体
基础原料
S1P Receptor
结构式 | 货号 | 产品名称 | CAS号 |
---|
BCP49679 | CYM-5478 新 | 870762-83-7 | |
CYM-5478 is a potent and highly selective S1P2 agonist with an EC50 of 119 nM in a TGFα-shedding assay. CYM-5478 protects neural-derived cell lines against Cisplatin toxicity.
|
BCP45657 | BMS-986278 新 | 2170126-74-4 | |
BMS-986278, a second-generation LPA1 antagonist, is currently in phase 2 development as a therapy for IPF and PF-ILD.
|
BCP45353 | TY-52156 新 | 934369-14-9 | |
TY-52156 is a potent and selective S1P3 receptor antagonist with a Ki value of 110 nM.
|
BCP44572 | CYM50358 新 | 1314212-39-9 | |
CYM50358 is a potent, selective antagonist of the sphingosine-1-phosphate receptor 4 (S1P4).
|
BCP42260 | MUN96006 新 | 2130996-00-6 | |
MUN96006 is an antagonists of sphingosine-1-phosphate (S1P) receptor for prophylaxis and/or treatment of diseases including fibrotic, inflammatory, autoimmune, metabolic, cardiovascular, and/or proliferative diseases.
|
BCP41026 | S1P1 Agonist III 新 | 1324003-64-6 | |
S1P1 Agonist III is a potent and selective sphingosine-1-phosphate receptor 1 (S1P1) agonist.
|
BCP39849 | PF429242 dihydrochloride 新 | 2248666-66-0 | |
PF 429242 is a reversible and competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM), a transcriptional regulators of cholesterol, fatty acid, and glucose metabolism.
|
BCP38982 | W146 trifluoroacetate salt 新 | 909725-62-8 | |
W146 is a potent, selective S1P1 antagonist with Ki of 18 nM, displays no effect at S1P2, S1P3 or S1P5, enhances capillary leakage and restores lymphocyte egress in vivo. .
|
BCP38980 | RP101075 新 | 1306760-73-5 | |
RP101075 is a metabolite of ozanimod (GLXC-10658), exhibiting a similar specificity profile as ozanimod at the S1P receptor family in vitro and pharmacodynamic profile in vivo
|
BCP37989 | VPC 23019 新 | 449173-19-7 | |
VPC 23019 is an aryl amide-containing S1P analog that acts as a competitive antagonist, inhibit S1P-induced migration of thyroid cancer cells, ovarian cancer cells, and neural stem cells.
|