马来酸氟吡汀

参考资料仅供科学研究，不可用于个人用途。

货号：BCP02202CAS号：75507-68-5纯度：98%

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CAS号	75507-68-5	货号	BCP02202
中文名	马来酸氟吡汀
英文名	Flupirtine maleate
中文别名
英文别名	D 9998;D-9998;D9998;Katadolon;Keiton;
SMILES
化学名称
分子式	C19H21N4O6F	分子量	420.4
纯度	98%	配送	惯例下常温包邮
产品描述	Flupirtine pre-incubated for 2 hours prevents cell death in rat cortical neurons induced by NMDA and gp120 of HIV-1. Flupirtine is capable of protecting primary neurons against glutamate-induced cytotoxicity by reducing calcium ion concentrations at 1-10 mM. Flupirtine pretreated for 2 hours preventsβ-amyloid-induced apoptosis in primary neuronal cells at concentrations of 1 or 5μg/mL. Flupirtine at concentration of 10 μM markedly decreases nonreceptor-mediated necrotic cell death in PC 12 cultures treated with 10 mM L-glutamate, meanwhile, Flupirtine exerts anti-oxidative effects in PC 12 cultures. Flupirtine-maleate at concentrations of 1 μM and 10 μM decreases TRAIL-mediated death of human living brain tissue culture. Flupirtine activates inwardly rectifying potassium ion channels and thus stabilizes the resting membrane potential at a therapeutically relevant concentration.