奥沙利铂

参考资料仅供科学研究，不可用于个人用途。

货号：BCP22716CAS号：61825-94-3纯度：98%

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CAS号	61825-94-3	货号	BCP22716
中文名	奥沙利铂
英文名	Oxaliplatin
中文别名	己草铂;左旋反式二氨环己烷草酸铂;
英文别名
SMILES	O=C(O[Pt]O1)C1=O.N[C@]2[C@](N)CCCC2
化学名称
分子式	C8H12N2O4Pt	分子量	397.29
纯度	98%	配送	惯例下常温包邮
产品描述	Oxaliplatin is an organoplatinum complex in which the platinum atom is complexed with 1,2-diaminocyclohexane (DACH) and with an oxalate ligand as a 'leaving group.' A 'leaving group' is an atom or a group of atoms that is displaced as a stable species taking with it the bonding electrons. After displacement of the labile oxalate ligand leaving group, active oxaliplatin derivatives, such as monoaquo and diaquo DACH platinum, alkylate macromolecules, forming both inter- and intra-strand platinum-DNA crosslinks, which result in inhibition of DNA replication and transcription and cell-cycle nonspecific cytotoxicity. The DACH side chain appears to inhibit alkylating-agent resistance. Check for active clinical trials or closed clinical trials using this agent.