PF 562271 苯磺酸盐

参考资料仅供科学研究，不可用于个人用途。

货号：BCP14770CAS号：939791-38-5纯度：98%

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CAS号	939791-38-5	货号	BCP14770
关联产品	717907-75-0（PF-562271） 939791-41-0（PF562271 Hydrochloride）
中文名	PF 562271 苯磺酸盐
英文名	PF-562271 benzenesulfonate
中文别名
英文别名	PF562271; PF562271; PF-562271; PF-00562271; PF00562271; PF 00562271;PF562271 benzesulfonate salt;; PF562271 besylate;
SMILES
化学名称
分子式	C21H20F3N7O3S.C6H6O3S	分子量	665.67
纯度	98%	配送	惯例下常温包邮
产品描述	PF-562271 (besylate) is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 kinase with IC50 of 1.5 nM and 13 nM, and has > 100-fold selectivity against other protein kinases, except for some CDKs.PF-562271, also known as PF-562,271, is an orally bioavailable small molecule and ATP-competitive focal adhesion kinase (FAK) inhibitor with potential antineoplastic and antiangiogenic activities. PF-562271 inhibits the tyrosine kinase FAK, and to a lesser extent, proline-rich tyrosine kinase (PYK2), which may inhibit tumor cell migration, proliferation, and survival. Note: PF-562271 benzesulfonate is also called PF-562271 besylate.