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Aurora

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Aurora

结构式 货号 产品名称 CAS号
Tinengotinib 结构式
 BCP49223 Tinengotinib 2230490-29-4
Tinengotinib is an antineoplastic tyrosine kinase inhibitor.Tinengotinib is the modulator of one or more protein kinases such as Aurora kinase and VEGFR kinase.
Aurora Kinase Inhibitor II 结构式
 BCP48936 Aurora Kinase Inhibitor II 331770-21-9
Aurora Kinase Inhibitor II is a selective and ATP-competitive Aurora kinase inhibitor with IC50s of 310 nM and 240 nM for Aurora A and Aurora B, respectively.
SP-146 结构式
 BCP48903 SP-146 2682114-54-9
SP-146 is a potent, selective and non-ATP-competitive inhibitor of Aurora B with IC50 of 0.316 nM. SP-146 can be used for the research of triple negative breast cancer (TNBC).
Aurora B inhibitor 1 结构式
 BCP42843 Aurora B抑制剂1 937276-52-3
Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor extracted from patent WO2007059299A1, compound 1-3, has a Ki value of <0.010 uM.
SP-146 结构式
 BCP35921 SP-146 SP-146
SP-146 is a potent, selective and non-ATP-competitive inhibitor of Aurora B with IC50 of 0.316 nM.
Phthalazinone pyrazole 结构式
 BCP33311 Phthalazinone pyrazole 880487-62-7
Phthalazinone pyrazole is a potent, selective and orally bioavailable inhibitor of Aurora-A kinase.
结构式
Aurora Kinase Inhibitor III 结构式
 BCP30248 Aurora Kinase Inhibitor III 879127-16-9
Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).
Cenisertib 结构式
 BCP28083 Cenisertib 871357-89-0
Cenisertib selectively binds to and inhibits aurora kinases (AKs), a family of serine-threonine kinases which are important regulators of cell division and proliferation, and which are overexpressed in certain types of cancer.
CCT241736 结构式
 BCP29563 CCT241736 1402709-93-6
CCT241736 is a novel, orally bioavailable, imidazo[4,5-b]pyridine derivative discovered at our Institute, highly selective for FLT3 and Aurora kinases with an S(10) selectivity score using KINOMEscan™ technology of 0.057 (fraction of 386 non-mutant kinases inhibited >90% when screened at 1 uM of CCT241736; San Diego, CA).
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