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结构式 货号 产品名称 CAS号
MTX115325 结构式
BCP49673 MTX115325 2750895-97-5
MTX115325 is an orally active, brain-penetrating USP30 inhibitor (IC50=12 nM) with neuroprotective activity.
ARV393 结构式
BCP49670 ARV393 2851885-95-3
ARV-393 is an orally active PROTAC degrader targeting BCL6. ARV-393 utilizes the ubiquitin-proteasome system to target the degradation of BCL6. ARV-393 has DC50 and GI50 values of <1 nM in multiple cell lines of diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma (BL). ARV-393 also demonstrated considerable tumor suppressor activity in tumor xenograft models.
Hematin porcine 结构式
BCP49671 羟高铁血红素 15489-90-4
Hematin is an iron-containing porphyrin. It is used for testing in vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens.
RMC-7977 结构式
BCP49669 泛KRAS抑制剂 2765082-12-8
RMC-7977 is a reversible, tri-complex RAS inhibitor with broad spectrum activity for both mutant and wild-type (WT) KRAS, NRAS, and HRAS variants.
N-tert-Butyl-α-phenylnitrone 结构式
BCP49663 N-叔丁基-α-苯基硝酮 3376-24-7
N-tert-Butyl-α-phenylnitrone is a nitrone-based free radical scavenger that forms nitroxide spin adducts.
TH-Z154 结构式
BCP49660 TH-Z154 2260887-57-6
TH-Z145, a lipophilic bisphosphonate, is a FPPS inhibitor (IC50: 210 nM).
Ninerafaxstat 3HCl 结构式
BCP49659 Ninerafaxstat 3HCl 2311824-72-1
Ninerafaxstat trihydrochloride shifts cellular metabolism to glucose oxidation from fatty acid oxidation. Ninerafaxstat trihydrochloride improves overall mitochondrial respiration and reduces fatty acid oxidation, thereby inhibiting the proliferation and growth of cancer cells.
ZK53 结构式
BCP49658 ZK53 3031789-26-8
ZK53 is a selective and potent activator of mitochondrial casein hydrolase protease P (HsClpP).ZK53 induces apoptosis and inhibits the hydrolysis of alpha-casein by HsClpP.ZK53 inhibits tumour growth in xenografts and native mouse models.
TH-Z93 结构式
BCP49657 TH-Z93 2260887-09-8
TH-Z93, a lipophilic bisphosphonate, is a FPPS inhibitor (IC50: 90 nM).
Azvudine 结构式
BCP34041 阿兹夫定 1011529-10-4
Azvudine is a nucleoside reverse transcriptase inhibitor (NRTI), which exhibits inhibtory effects on HIV, HBV and HCV.
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